Research Data Published in Annals of Surgery Concludes Irreversible Electroporation Utilizing NanoKnife Results in Substantially Prolonged Survival for Patients With Locally Advanced Pancreatic Cancer Compared With Historical Controls

Thursday, August 13, 2015

Source: AngioDynamics

AngioDynamics (NASDAQ:ANGO), a leading provider of innovative, minimally invasive medical devices for vascular access, surgery, peripheral vascular disease and oncology, announced today the publication of clinical data from STAR (Soft Tissue Ablation Registry) utilizing NanoKnife®, in the Annals of Surgery.

The published paper entitled: Treatment of 200 Locally Advanced (Stage III) Pancreatic Adenocarcinoma Patients With Irreversible Electroporation, Safety and Efficacy appears in the September 2015 online edition of the peer-reviewed journal. STAR was first presented at the American Surgical Association annual meeting in San Diego earlier this year as an analysis of Irreversible Electroporation (IRE) performed on 200 consecutive patients diagnosed with locally advanced pancreatic cancer (LAPC).

The authors of the paper, led by Robert Martin, M.D., Ph.D., F.A.C.S., director of the Division of Surgical Oncology, and Professor, Department of Surgery, University of Louisville, James Graham Brown Cancer Center, stated in the paper's conclusion that they believe, "IRE results in substantially prolonged survival of patients with LAPC compared with historical controls."

The paper states that the goal of the study was to evaluate the effectiveness of IRE as a consolidative therapy in combination with chemotherapy and/or chemoradiation therapy in the management of LAPC.

Pancreatic cancer has one of the highest mortality rates of all cancers and is expected to climb from the fourth leading cause of cancer-related death in the U.S. to the second by 2020. Ninety-four percent of pancreatic cancer patients will die within five years of diagnosis, and 74 percent of patients die within the first year of diagnosis.

The study was partially funded by a grant provided by AngioDynamics.

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